EMMD - Electrochemistry, Molecular Materials and Devices

EMMD (Electrochemistry, Molecular Materials and Devices) research activities are devoted to molecular materials, from molecules to materials and from materials to devices. Electrochemical techniques are used to synthesize, to immobilize and to detect chemical or biological species. The synthetic aspect relates to the synthesis and functionalization of macrocycles (porphyrins, phthalocyanines…) and polymers. The analytical aspect 1) exploits the redox properties of compounds or sensitive layers (biomaterials, conducting polymers, charge-transfer complexes, …) for the characterization and the detection of biomolecules or chemical pollutants in sensor devices; 2) to apprehend reaction mechanism of molecular processes. Our projects are focused on applications in the fields of environment, health and food industry.

MALACEA KABBARA Raluca Voir la fiche profil en français Français (FR)

image-profil
  • MALACEA KABBARA Raluca
  • Statut : Researcher (CR-HDR)
  • Team : OCS
  • Function : Researchers
  • Tags : Catalysis, Coordination chemistry, Molecular imaging, Organometallic chemistry
  • ORCID : 0000-0002-6684-1967
  • Address :

    ICMUB Institut de Chimie Moléculaire de l'Université de Bourgogne
    Bât. MIRANDE - Aille B - Bureau B-220
    9 Avenue Alain Savary
    21000 Dijon – France

  • Tél : (+33) 380 399 038
  • raluca.malacea@u-bourgogne.fr

Habilitation - Bourgogne Franche-Comté University (2018)
CNRS researcher - Institute of Molecular Chemistry of the University of Burgundy (since 2009)
PhD in Organometallic Chemistry and Coordination - University Paul Sabatier, Toulouse (2006)
Master in Organic Chemistry- Polytechnic School of Bucharest (2001)
Chemical Engineer Diploma - Polytechnic School of Bucharest (2000) 

Heterofunctionalized amino acids for PET (positron emission tomography) imaging
Metal complexes for bioinorganic applications
Chiral titanocenes for catalysis
Unsymmetrical ruthenium complexes of functionalized phosphines  

34 A new Route toward (Aminomethyl)cyclopentadienide Ligands and their Group 4 Metal Complexes, Eur. J. Inorg. Chem. 2018, 3813-3821
Quentin Bonnin, Sook-Yen Wong, Cédric Balan, Virginie Comte, Raluca Malacea, Marie-José Penouilh, Philippe Richard, Gerald Kehr, Adrien Normand, Gerhard Erker, Pierre Le Gendre
33 Atom Transfer Radical Addition catalysed by Ruthenium-Arene Complexes bearing a Hybrid Phosphine-Diene Ligand. Organometallics 2018, DOI: 10.1021/acs.organomet.7b00851
Florian Chotard, Raluca Malacea-Kabbara, Cédric Balan, Ewen Bodio, Michel Picquet, Philippe Richard, Miguel Ponce-Vargas, Paul Fleurat-Lessard, Pierre Le Gendre
32 Designing Silylated L-Amino Acids using a Wittig Strategy: Synthesis of Peptide Derivatives and 18F-Labelling, Eur. J. Org. Chem. 2017, 5399-5409
Baptiste Rugeri, Hassib Audi, Pawel Jewula, Radouane Koudih, Raluca Malacea-Kabbara, Delphine Vimont, Jürgen Schulz, Philippe Fernandez, Sylvain Jugé
31 o-BF3-Phosphonium pincer moieties in the design of delocalized lipophilic cation based tracers for PET imaging of mitochondrial function. J. Nucl. Med. 2017, 58, 482-483
Shubhanchi Nigam, Juozas Domarkas, Julie Bernard, Goncalo Clemente, Benjamin Burke, Sylvain Juge, Raluca Malacea-Kabbara, David Benoit, Christopher Cawthorne, Steve Archibald
30 [18F]Fluoride radiolabelling and stability of B-F…P pincer triphenylphosphonium derivatives for applications in mitochondrial imaging.J. Nucl. Med. 2015, 5, 636.
Shubhanchi Nigam, Gonçalo Clemente, Julie Bernard, Raluca Malacea-Kabbara , Sylvain Jugé, Benjamin Burke, Anne-Marie Seymour, Chris Cawthorne, Steve Archibald
29 Ketone Hydrogenation with Iridium Complexes with “non N-H” Ligands: the Key Role of the Strong Base, ACS Catal. 2015, 5, 4368–4376
Joseph Hayes, Eric Deydier, Gregori Ujaque, Agustí Lledós, Raluca Malacea-Kabbara, Eric Manoury, Sandrine Vincendeau, Rinaldo Poli
28 Efficient Stereoselective Synthesis of Boron L-Amino acid Derivatives Using Wittig and Borylation Reactions, Phosphorus, Sulfur Silicon Relat. Elem. 2015, 190, 953-954
Hassib Audi, Emmanuelle Rémond, Marie-Joëlle Eymin, Arnaud Tessier, Raluca Malacea-Kabbara, Sylvain Jugé
27 Phosphonium-Boronate Amino acid Derivatives as Fluoride Pincers for 18F-Labelling; Phosphorus, Sulfur Silicon Relat. Elem. 2015, 190, 957-958
Julie Bernard, Goncalo Clemente, Benjamin P. Burke, Marie-Joëlle Eymin, Stephen J. Archibald, Raluca Malacea-Kabbara, Sylvain Jugé
26 o-Boronato- and o-Trifluoroborato-Phosphonium Salts Supported by L-α-Amino Acid Side Chain, J. Org. Chem. 2015, 80, 4289–4298
Julie Bernard, Raluca Malacea-Kabbara, Gonçalo S. Clemente, Benjamin P. Burke, Marie-Joëlle Eymin, Stephen J. Archibald, Sylvain Jugé
25 Efficient Synthesis of (P-Chiral) o-Boronated Phosphines from sec-Phosphine Boranes, Org. Lett. 2015, 17, 1216–1219
Jerome Bayardon, Julie Bernard, Emmanuelle Rémond, Yoann Rousselin, Raluca Malacea-Kabbara, Sylvain Jugé
24 Modular Hemisyntheses of Boronato- and Trifluoroborato L-NHBoc Amino Acid and Peptide Derivatives, Eur. J. Org. Chem. 2013, 7960-7972
Hassib Audi, Emmanuelle Rémond, Marie-Joëlle Eymin, Arnaud Tessier, Raluca Malacea-Kabbara, Sylvain Jugé
23 ortho-(Dimesitylboryl)phenylphosphines: Positive Boryl Effect in the Pd-catalyzed Suzuki-Miyaura Coupling of 2-Chloropyridines, Adv. Synth. Catal. 2013, 355, 2274-2284
Raluca Malacea, Faouzi Chahdoura, Marc Devillard, Nathalie Saffon, Montserrat Gómez, Didier Bourissou
22 Combining planar and central chirality in ferrocene thiophosphine-sulfoxides, Tetrahedron: Asymmetry2013, 24, 612-620,
Raluca Malacea, Jean-Claude Daran, Rinaldo Poli, Eric Manoury
21 Synthetically Derived Auxiliaries: Phosphorus Derivatives, Comprehensive Chirality 2012, 3, 528-559(Edited by Carreira, Erick M.; Yamamoto, Hisashi)
Sylvain Juge, Raluca Malacea, Arnaud Tessier
20 Ruthenium–alkylidene catalysed cross-metathesis of fatty acid derivatives with acrylonitrile and methyl acrylate: a key step toward long-chain bifunctional and amino acid compounds, Green Chem. 2011, 13, 2911-2919
Xiaowei Miao, Raluca Malacea, Cedric, Fischmeister, Christian Bruneau, Pierre H. Dixneuf
19 A new insight into ortho-(dimesitylboryl)diphenylphosphines: applications in Pd-catalyzed Suzuki-Miyaura couplings and evidence for secondary π-interaction, Chem. Commun.2011, 47, 8163-8165
Raluca Malacea, Nathalie Saffon, Montserrat Gomez, Didier Bourissou
18 Cross-metathesis with acrylonitrile and applications to fatty acid derivatives , Eur. J. Lipid Sci. Tech. 2010, 112, 3-9
Christian Bruneau, Cedric Fischmeister, Xiaowei Miao, Raluca Malacea, Pierre H. Dixneuf
17 Asymmetric hydrosilylation, transfer hydrogenation and hydrogenation of ketones catalyzed by iridium complexes, Coord.   Chem. Rev.2010, 254, 729-752
Raluca Malacea, Rinaldo Poli, Eric Manoury
16 Alkene metathesis and renewable materials: selective transformations of plant oils” in Green Metathesis Chem. Springer 2010, 185-206
Raluca Malacea, Pierre Dixneuf
15 Renewable materials as precursors of linear nitrile-acid derivatives via cross-metathesis of fatty esters and acids with acrylonitrile and fumaronitrile, Green Chem. 2009, 11, 152-155
Raluca Malacea, Cédric Fischmeister, Jean-Luc Dubois, Jean-Luc Couturier, Christian Bruneau, Pierre H. Dixneuf
14 Synthesis and structure of Pt(0) and Pt(II) complexes supported by chiral fereocenyl (P,S) ligands, J. Mol. Str. 2008, 890, 249-254
Raluca Malacea, Eric Manoury, Jean-Claude Daran, Rinaldo Poli
13 Ruthenium allenylidenes and indenylidenes as catalysts in alkene metathesis; Allenylidenes and Vinylidenes in Catalyis, Wiley-VCH, 2008, 251-278
Raluca Malacea, Pierre H. Dixneuf
12 “Phosphporus sulfur ligands” in Trivalent Phosphorus Compounds in Asymmetric Catalysis, Synthesis and Applications, A. Börner Eds. Wiley-VCH, 2008, 749-784
Raluca Malacea,Eric Manoury
11 Palladium and Platinum Complexes with Planar Chiral 1,2-disubstituted ferrocenes containing phosphine and thioether donor groups, J. Organomet. Chem. 2008, 693, 1469-1477
Raluca Malacea, Lucie Routaboul, Eric Manoury, Jean-Claude Daran, Rinaldo Poli
10 Catalytic three-phase diastereoselective hydrogenation of o-toluic and 2-methyl nicotinic acid derivatives: In-situ FTIR/ATR investigation, Vibrational Spectroscopy 2007, 45, 18-26
Albin Pintar, Raluca Malacea, Catherine Pinel, Michele Besson
9 Highly efficient asymmetric hydrogenation of alkyl aryl ketones catalyzed by iridium complexes with chiral planar ferrocenyl phosphino-thioether ligands, Adv. Synth. Catal.2007, 349, 309-313
Erwan Le Roux, Raluca Malacea,Eric Manoury, Rinaldo Poli, Luca Gonsalvi, Maurizio Peruzzini.
8 Parahydrogen studies of H2 addition to Ir(I) complexes containing a chiral phosphine-thioether ligand: Implications for catalysis, Dalton. Trans. 2006, 27, 3350-3359
Raluca Malacea, Jean-Claude Daran, Simon B. Duckett, John P. Dunne, Cyril Godard, Eric Manoury, Rinaldo Poli and Adrian C. Whitwood
7 Coordination chemistry and diphenylacetylene hydrogenation catalysis of planar chiral ferrocenyl phosphine-thioether ligands with cyclooctadieneiridium(I) Eur. J. Inorg. Chem. 2006, 1803-1816
Raluca Malacea, Eric Manoury, Lucie Routaboul, Jean-Claude Daran, Rinaldo Poli, John P. Dunne, Adrian. C. Withwood, Cyril Godard, Simon. B. Duckett.
6 A new class of rhodium(I) к1-P and к2-P,N complexes with rigid PTN(R) ligands (ptn = 1,5,7-triaza-3-phosphabicyclo[3.3.1]-nonane, R = Me, Ph),Organometallics2006, 25, 2189-2200
Andrew D. Phillips, Luca Gonsalvi, Maurizio Peruzzini, Jean-Claude Daran, Raluca Malacea, Rinaldo Poli.
5 Diastereoselective hydrogenation of a cyclic β-ketoformyl derivative on supported metal catalysts,J. Mol. Catal. A: Chem.2005, 227(1-2), 125-131
Raluca Malacea, Mircea Banciu, Mircea Pop, Michele Besson, Catherine Pinel.
4 In situ monitoring of catalytic three-phase enantioselective hydrogenation using FTIR/ATR spectroscopy, Appl. Catal. A 2004, 264(1), 1-12
Albin Pintar, Raluca Malacea, Catherine Pinel, Gabriella Fogassy, Michele Besson.
3 Heterogeneous diastereoselective hydrogenation of pyridine and corresponding enamine covalently bound to pantolactone, J. Mol. Catal. A: Chem.2004, 210(1-2), 205-209
Najiba Douja, Raluca Malacea, Michele Besson, Catherine Pinel.
2 Diastereoselective heterogeneous catalytic hydrogenation of 2-methylnicotinic acid using pyroglutamate chiral auxiliary, Tetrahedron Lett. 2003, 44(37), 6991-6993
Najibe Douja, Raluca Malacea, Mircea Banciu, Michele Besson, Catherine Pinel.
1 Flow-vacuum pyrolysis of 2,5-diphenyl-4-methyloxazole, Rev. Roum. Chimie2003, 47(5), 493-498
Mircea Banciu, Daniela Istrati, Iosif Schiketanz, Dan Mihaiescu, Constantin Draghici, Raluca Malacea.

19 oral communications including 14 as a speaker (from which 3 were on invitation)
25 poster communications

Organic Chemistry and Stereochemistry (1st and 3rd year of Chemistry) since
2013 Teaching in Organic Chemistry -Fournier Laboratories (Inventiva), Daix (2010-2012) - continuing education
Pharmacognosy - Faculty of Pharmacy - University of Burgundy (2011)
Organic Chemistry, IUT Castres / University Paul Sabatier (2008)